Indian Researchers Have Found A Way to Kill Antibiotic Resistant Bacteria

In News

Indian researchers have identified a protein pathway in an antibiotic resistant bacterial strain and developed a new molecule to target this pathway.


  • In a collaborative effort, scientists from CSIR-Central Drug Research Institute (CDRI), Lucknow and Indian Institute of Science Education and Research (IISER), Pune have identity the protein pathway in Staphylococcus aureus (S. aureus).
  • The new molecule developed was indole based quinone epoxide (IND-QE).
  • The molecule can travel through the cell barriers and target MarR proteins, the essential proteins for the growth of S. aureus bacteria.
  • The development comes at a time when antimicrobial resistance is becoming a global challenge and developing new antibiotics is becoming a challenge.

The Discovery

  • In general, new antibiotics are prepared from natural products like fungal extracts or plant extracts or from large chemical libraries.
  • But, the researchers involved in the development of the molecule selected a less-explored process of antibiotic discovery.
  • The bacteria S. Aureus is commonly found on human skin and mucosal membranes.
  • The bacteria can cause severe infections like endocarditis, osteomyelitis or pneumonia, etc., if it enters the bloodstream.
  • The bacteria can readily become resistant to antibiotics.
  • The IND-QE molecule destroys the MarR proteins of the bacteria thereby hampering its growth.


Drug discovery is the ultimate step in the fight against antibiotic resistant bacteria. The discovery of a new molecule to kill a resistant bacteria comes at the right time.

About Classic IAS Academy 532 Articles
Classic IAS Academy is at the forefront of providing best IAS coaching in delhi, India. The Academy helps the aspirants to tap their innate analytical power to become successful in the exam.

Be the first to comment

Leave a Reply